With a “wah wah” cry, Ms. Zhang’s child was born, the family was immersed in happiness. But the careful Ms. Zhang found that the child’s lips, fingers and toes were purple, and black when crying; shortness of breath, less milk, and no weight gain. The family panicked and rushed the child to the hospital for a checkup, which showed that the child had a serious and complicated congenital heart disease. The causes of congenital heart disease congenital heart disease is a cardiovascular malformation that occurs in the fetus during the embryonic period due to abnormal cardiovascular development, and is the most common heart disease in infants and children. 0.8% of newborn infants will suffer from this disease, the causes of congenital heart disease in infants and children are still unclear, but mainly due to genetic and environmental factors and their interaction: single gene and chromosomal abnormalities, intrauterine infection, exposure to radiation , history of drug use (anticancer drugs, antiepileptic drugs, etc.), metabolic disorders (e.g., diabetes), and alcohol and drug abuse in early pregnancy. With the rapid development of cardiovascular science, many common congenital heart diseases can be accurately diagnosed and reasonably treated, and the death rate has been significantly reduced. It is not impossible for congenital heart disease to heal itself, but the probability is relatively small. Patients with small ventricular septal defects may have a chance of healing themselves before the age of 2, but the majority of patients still need to rely on surgery for treatment. The main clinical manifestations are cardiac insufficiency and dysplasia. The diagnosis can be made by symptoms, signs, electrocardiogram, X-ray and echocardiogram, and the hemodynamic changes, degree and extent of the lesion can be estimated to determine the treatment plan. For combined with other anomalies and complex precordial disease, we can combine with cardiac catheterization or cardiovascular imaging to understand the degree, type and scope of abnormal lesions, make a comprehensive analysis, make a clear diagnosis, and develop a treatment plan. Prenatal can diagnose whether the fetus has congenital heart disease More than 85% of fetuses with congenital heart disease can be detected in the embryonic period through prenatal screening and detection, and the echocardiography can be used to predict the condition of the fetal heart, thus also avoiding the birth of some fetuses with complex heart malformations. Currently, the national standard for prenatal fetal screening is divided into two steps: at 14-20 weeks of gestation, the fetus receives a routine obstetric ultrasound to perform an initial screening of the fetal heart. Once problems are identified, the fetus is subjected to an echocardiogram, which is usually performed between 18-28 weeks, the best time for fetal echocardiographic exploration. Fetal echocardiography should be performed if there is a family history of preexisting heart disease, if the obstetrician listens to an irregular fetal heartbeat or if the fetus is conceived in advanced maternal age. Diagnosis with echocardiography is effective in screening for precocious heart disease, and the diagnosis usually takes only a few minutes and has no effect on the fetus.