How is a kidney infection treated? A kidney infection is what is referred to as a urinary tract infection. Pyelonephritis is an infection of the upper urinary tract, and it is a more serious urinary tract infection. The vast majority of pathogens are bacterial, with Escherichia coli being the most common, making the use of adequate doses, courses, and standardized antibiotics particularly important. Before the conclusion of urine culture, empirical treatment is usually used first, such as choosing quinolone antibiotics, such as levofloxacin, and also cephalosporins, such as cefuroxime, and adjusting the treatment according to the drug sensitivity after the results of urine culture test. Antibiotics should be used for 7-14 days. Patients with heavy systemic symptoms can consider IV treatment, which can be changed to oral when the body temperature is normal, and patients with lighter types can directly take the drugs orally. Complex types can extend the antibiotics all the way up to six weeks, and recurrent, relapsing ones can also consider long course, low dose antibacterial therapy for six months. Like one tablet of cefuroxime or one tablet of levofloxacin, taken at bedtime and exchanged every 7-10 days for six months. In addition to medication, drinking more water, urinating regularly and not holding urine are also the most basic treatments.