Chronic interosseous vein thrombosis can be partially cured, and the treatments include medications such as heparin and warfarin, and surgical treatments such as thrombectomy and ligation. 1. Drug treatment: chronic interosseous vein thrombosis should be treated with anticoagulant drugs such as low molecular heparin, warfarin, rivaroxaban and so on according to the doctor’s prescription, so as to prevent the spread of thrombus. During the period of drug treatment, the coagulation function should be rechecked regularly, and the medication should be adjusted according to the test results to avoid bleeding. Some patients can be cured after 3-6 months of anticoagulation. 2. Surgery: When chronic interstitial vein thrombosis is serious, surgical treatment such as thrombectomy, ligation, radiofrequency surgery can be chosen according to medical advice. Surgery can effectively remove the thrombus and avoid serious consequences caused by thrombus dislodgement. Chronic interstitial vein thrombosis should be treated promptly by a doctor after examination and evaluation to avoid delaying the condition. After active treatment, the thrombus is cleared and can be considered clinically cured. However, aspirin and warfarin should be taken on a daily basis to prevent the thrombus from forming again.