Diabetic patients with numbness and tingling on the soles of the feet should first clarify the cause of the disease and then treat the cause. It may be caused by the complication of diabetic neuropathy, diabetic foot and other diseases, which can be dealt with by the basic comprehensive treatment, medication, braking and decompression, and surgical treatment, etc. It is recommended that you consult your doctor. 1. Diabetic neuropathy: Patients may experience abnormal sensory symptoms such as numbness, burning, and pins and needles sensation in the extremities. Treatment by insulin injection, with diet and exercise therapy based on the use of nutritional nerve, improve microcirculation and other symptomatic treatment, commonly used drugs such as methylcobalamin tablets. 2. Diabetic foot: the main symptoms include pinprick pain and numbness at the end of the toes, etc. Patients need to be treated on the basis of systemic therapy, vasodilatation, anticoagulation, thrombolysis, anti-infection and other treatments, and if necessary, surgical treatment. It is recommended that diabetic patients with numbness and tingling in the soles of the feet, go to the hospital in time to avoid adverse consequences.