There is no such thing as the most effective medication for gout. Drugs for gout mainly include non-steroidal anti-inflammatory drugs (e.g. indomethacin), colchicine, glucocorticoids (e.g. methylprednisolone), drugs to promote uric acid excretion (e.g. phenylbromarone), and drugs to inhibit uric acid production (e.g. febuxostat). It is recommended to take the medication as prescribed by the doctor. During acute gout attacks, NSAIDs such as indomethacin, diclofenac sodium, etoricoxib, etc.; small doses of colchicine; glucocorticoids such as methylprednisolone and prednisone acetate can be taken as prescribed by the doctor. In the intermittent and chronic period of gout attack, you can follow the doctor’s instructions to take to promote uric acid excretion drugs such as benzbromarone, probenecid, etc.; inhibit uric acid production drugs such as febuxostat, allopurinol, etc. to control the uric acid level, in order to improve the condition. All of the above drugs should be used under the guidance of a doctor, do not use them without authorization, so as not to cause adverse consequences. It is recommended that gout patients seek medical advice in a timely manner and follow the doctor’s instructions for standardized treatment.