1, first of all, see if you have the following high-risk factors: diabetes, smoking, hypertension, hyperlipidemia, hyperhomocysteinemia. Among them, diabetes and smoking should be emphasized. 2, there are no the following symptoms: lower limb atherosclerosis occlusive disease is generally seen in middle-aged and elderly people, early stage can have no obvious symptoms, or only slight discomfort, such as coldness, numbness, etc., and then gradually appear intermittent claudication symptoms, which is a characteristic symptom of lower limb atherosclerosis occlusive disease. “Appears when walking, relieved by stopping exercise, and reproduced by walking again”. After walking for a certain distance, muscle pain and weakness of the affected limb appears, and cramps, forcing the patient to stop and rest for 3-5 minutes; after resting, the symptoms can be completely relieved, and after walking the same distance again, the symptoms reappear, and the location of the pain correlates with the location of the vascular lesion, which can be manifested in the buttocks, thighs or calves, at which time the patient’s activities are gradually restricted, and we have many patients who are only 40 years old and can only walk 100 We have many patients in their 40s who can only walk 100 meters or so. The further development of the lesion will enter into a state of severe ischemia, then the distal limb resting pain will appear, that is, the pain of the limb exists when resting, and it will be heavier when lying down and resting at night, and the patient will have difficulty sleeping at night, and the more painful it is at the end of the night, the more the limb can become ulcerated, gangrene and infected, leading to amputation and death. 3. There are no manifestations of the following limb ischemia: cool, pale or bruised affected limbs, thinning skin, reduced sweat hair, thickened nails, weakened or absent arteries; toe ulcers, infections, gangrene. Those who have the above factors, especially those who have developed nighttime toe pain, ulcers and gangrene, and those whose lower limb ulcers do not heal with long-term medication changes, should go to the vascular surgery department of the hospital for appropriate examination and treatment as early as possible.