Patient: runny nose, coughing in the morning, phlegm, rumbling in the lungs, upper respiratory tract has a slight blockage of the symptoms of bronchial asthma in June 2008, about 07 days of treatment drip infusion, inhaled Sinebic Dupuyao half a month, and then use Pramic Dupuyao 2 months, cured in January 2009, the recurrence of the disease in Liaoyang City, the third hospital hospital in 20 days of treatment, confirmed as allergic asthma, after the examination of the allergen is the Household dust mite dust mite, cockroach allergy discharged from hospital. After 3 months of inhalation of Sulidian on January 14, 10, the disease recurred in the three hospitals stayed in the hospital for a month on February 8, discharged from the hospital on March 16, and feel the disease is about to break after examination of the hospital hospital drugs are methylprednisolone, doxophylline, first Shu, magnesium sulfide oral inhalation of Sulidian is being treated Laboratory, examination results. Hormones are the most effective drugs for controlling airway inflammation. Routes of administration include inhalation, oral and intravenous, with inhalation being the preferred route. Inhaled administration Inhaled hormones have a strong local anti-inflammatory effect; administered through the inhalation process, the drug acts directly on the respiratory tract and requires a smaller dose. Most of the drugs that enter the bloodstream through the digestive tract and the respiratory tract are inactivated by the liver, so there are fewer systemic adverse reactions. The results of the study proved that inhaled hormones are effective in reducing asthma symptoms, improving quality of life, improving lung function, reducing airway hyperresponsiveness, controlling airway inflammation, reducing the frequency and severity of asthma attacks, and decreasing morbidity and mortality. Different therapeutic effects may be produced when different inhalation devices are used. Most adults with asthma have good control of their asthma with small doses of inhaled hormones. Excessive increases in inhaled hormone doses have less benefit and more adverse effects on asthma control. Because smoking reduces the effectiveness of hormones, patients who smoke must stop smoking and be given higher doses of inhaled hormones. There is a clear relationship between the dose of inhaled hormones and the prevention of severe acute asthma attacks, so that long-term high-dose inhaled hormones are beneficial in patients with severe asthma. Adverse effects of inhaled hormones localized in the oropharynx include hoarseness, pharyngeal discomfort, and candida infections. Prompt gargling of the oropharynx with water after inhalation and the use of dry powder inhalers or the addition of a mist storage device can reduce these adverse effects. The magnitude of systemic adverse effects of inhaled hormones is related to the dose of the drug, the bioavailability of the drug, the absorption in the intestine, the rate of hepatic first-pass metabolism and the half-life of the systemically absorbed drug. Fluticasone propionate and budesonide have fewer systemic adverse effects among the marketed inhaled hormones. Current evidence suggests that adult asthmatics inhaling low to moderate doses of hormones daily do not experience significant systemic adverse effects. Systemic adverse effects that may occur after prolonged high-dose inhaled hormones include skin ecchymosis, adrenal suppression, and decreased bone density. There is evidence from studies that inhaled hormones may be associated with the development of cataracts and glaucoma, but there is no evidence from prospective studies of a clear association with the development of posterior subcapsular cataracts. There is no evidence that inhaled hormones increase the incidence of pulmonary infections (including tuberculosis), so asthmatics with active tuberculosis may be given inhaled hormone therapy along with antituberculosis treatment. Aerosol administration:Four types of inhaled hormones are commonly used in clinical practice, see Table 4. these include beclomethasone dipropionate, budesonide, and fluticasone propionate. In general, the use of dry powder inhalation devices is more convenient than regular dosing aerosols, and the amount of drug inhaled into the lower respiratory tract is higher. Solution administration:Budesonide solution is nebulized and inhaled through a jet device powered by compressed air, which does not require much inhalation cooperation from the patient and has a faster onset of action, and is suitable for the treatment of mild to moderate acute asthma attacks. Inhaled hormones are the drug of choice for the long-term treatment of asthma. Internationally recommended daily dose of inhaled hormone, see Table 4 China’s asthma patients need inhaled hormone dose is smaller than the recommended dose in Table 4.