Recently, I often encounter some patients in the clinic asking me “Can cirrhosis be completely cured?” In fact, liver cirrhosis has gone through the process of liver fibrosis, pathologically liver fibrosis is divided into 0, 1, 2, 3, 4 levels, level 0 is normal, from level 1 to level 4 belongs to the process of gradual aggravation, to level 4 is early cirrhosis, at this time the liver has not been completely deformed, can be completely cured, if liver fibrosis continues to progress, it will reach the middle and late stage, at that time the liver structure completely changed If the liver fibrosis continues to progress, the liver structure will be completely changed, and pathologically a large “pseudolobule” will be formed, and the liver will enter a state where there is no way to reverse it, which can be understood as a fresh liver being “cooked”. Can it be restored to a “raw egg”? The answer is definitely not possible. However, although it can not be reversed, control the further progress of liver disease today’s medicine still has a way, especially viral hepatitis B in recent years through antiviral treatment and active liver preservation, anti-fibrosis treatment, hepatitis B cirrhosis after the patient can be maintained in a long-term “subhealthy” state, liver function remains normal, so Such patients should not be pessimistic and desperate, but should seek professional treatment from a specialist regularly. Yuan Gang, Department of Hepatology, Ningbo Second Hospital