There is no drug that can cure osteoarthritis, and most of the drugs can only relieve the symptoms caused by osteoarthritis, such as non-steroidal anti-inflammatory, vasodilator drugs, nutritive chondroitics, and drugs injected into the joint cavity. 1. Non-steroidal anti-inflammatory drugs: the main role of pain relief, the mechanism of action for the inhibition of inflammatory mediators in the process of inflammatory response, so as to achieve the effect of reducing or inhibiting the inflammatory response. Representative drugs such as ibuprofen, meloxicam and so on. 2. Vasodilators: the mechanism of action is to change the permeability of blood vessels, thus causing the expansion of blood vessels and accelerating local blood circulation. They can be categorized into topical drugs and oral drugs, representing drugs such as Diosmin tablets. 3. Nutritional cartilage drugs: the main role of nutritional cartilage. The mechanism of action is to combine with macromolecular proteins in normal cartilage tissues, and to provide essential substances for cartilage synthesis. Representative drugs such as glucosamine hydrochloride, glucosamine sulfate and so on. 4. Drugs injected into the joint cavity: mainly divided into closed treatment and joint fluid component injection drugs. Closed treatment, i.e. closed needle, will be injected after mixing local anesthetic and glucocorticoid, representing drugs such as lidocaine and dexamethasone. The main purpose of joint fluid injection is to increase joint fluid and lubricate the joints, represented by drugs such as sodium vitrate. The above drugs need to be used under the guidance of a doctor, avoid self-medication.