Hyperthyroidism (referred to as hyperthyroidism) is a group of common endocrine diseases caused by excessive secretion of thyroid hormones from various causes. The main clinical manifestations of hyperthyroidism are: hyperphagia, emaciation, aversion to heat, excessive sweating, palpitations, agitation and other hypermetabolic syndromes, increased neurological and vascular excitation, and different degrees of goiter, eye protrusion, hand tremors, tibial vascular murmurs, etc. In severe cases, hyperthyroidism can lead to critical phase, coma or even life-threatening. The most common type of hyperthyroidism is diffuse goiter with hyperthyroidism, which accounts for about 90% of all hyperthyroidism. The ratio of male to female is 1:4. Hyperthyroidism is a common and multifaceted disease, which is divided into primary hyperthyroidism (proptosis goiter), secondary hyperthyroidism, goiter, and high-functioning adenoma. Primary hyperthyroidism is the most common and is an autoimmune disease, while secondary hyperthyroidism is less common and is caused by nodular goiter. Hyperthyroidism treatment: There are three classic treatments for hyperthyroidism: drugs, surgery, and isotopes. Minimally invasive ablation therapy can be considered for hyperthyroidism that cannot be cured by long-term medication: minimally invasive surgery focuses on the improvement and rehabilitation of patients’ psychological, social, physiological (pain), spiritual appearance, and quality of life, so as to be considerate of patients and reduce their pain to the greatest extent. Compared with traditional open surgery, minimally invasive surgery for hyperthyroidism has the following incomparable advantages: 1) less pain for patients 2) faster postoperative recovery: minimally invasive surgery for hyperthyroidism has a shorter postoperative hospital stay, usually 2-3 days; 3) lower surgical costs: because of the small chance of infection and short hospital stay, surgical costs are relatively lower. Minimally invasive surgery for hyperthyroidism should be less risky than traditional surgery, because the trauma to the patient is relatively small and the damage to the body tissue is also relatively small. At present, our group has performed many cases of hyperthyroidism ablation with good results, and the patient’s postoperative recovery is good, with thyroid function gradually returning to normal within 3 months.