Ejaculation in middle age may be caused by physiological factors, psychological factors and inflammatory diseases, etc. It is recommended that further examination be conducted to take appropriate behavioral therapy and drug treatment. 1. If there is no sexual intercourse for a long period of time, semen leakage may occur during deep sleep, which is generally regarded as a normal physiological reaction once every one or two weeks, and does not require any special treatment. 2. If it is due to frequent contact with audio-visual videos and other sexual stimuli, often have pornographic impulses or masturbation habits, the cerebral cortex is often in a state of excitement, can also lead to spermatorrhea, at this time you need to change the unhealthy habits, to avoid pornographic books, paintings, videos, reduce masturbation, and participate in appropriate sports and recreational activities to enhance physical fitness. 3. If further examination is due to prostatitis, circumcision and glansitis and other inflammatory diseases resulting in seminal emission, it is recommended to use drugs such as levofloxacin under the guidance of a doctor for the cause of the disease, or circumcision and other surgical procedures to be treated. All of the above situations require professional physicians to individualize the treatment plan according to the patient’s specific condition. Therefore, it is recommended to have a further examination in time and take appropriate treatment under the guidance of a doctor.