A period without bleeding and a wipe of blood may be caused by menorrhagia, abnormal bleeding related to pregnancy, polycystic ovary syndrome, hyperprolactinemia, etc. It is necessary to pay attention to this and visit a specialist to clarify the cause and give proper treatment and handling. Common causes and treatment 1. Abnormal pregnancy-related bleeding: If a woman has a history of sexual intercourse, consider that it may be due to abnormal uterine bleeding caused by pregnancy, rather than menstrual bleeding. It is recommended that women use ovulation test strips or go to the hospital for a blood HCG test to determine if they are pregnant. If pregnancy-related bleeding is diagnosed, it should also be clarified whether it is pre-eclampsia or ectopic pregnancy, etc. Corresponding treatment should be given after clear diagnosis; 2. Hypomenorrhea: Clarify the causes of hypomenorrhea, such as polycystic ovary syndrome or endometrial damage or premature ovarian failure, etc. If a woman suffers from polycystic ovary syndrome, it can be manifested as amenorrhea, scanty menstruation and gonorrhea, which may occur when there is no bleeding during menstruation and a rub of blood. Under the guidance of a doctor, drugs can be applied, such as taking compound levonorgestrel tablets to adjust the cycle, and ovulation-promoting drugs can be applied if there is a need for fertility; 3. Hyperprolactinemia: If a woman suffers from hyperprolactinemia, she can show menstrual disorders, secondary amenorrhea and reduced libido. It is recommended to check the MRI of butterfly saddle to exclude pituitary adenoma, etc. The treatment method is selected according to the serum prolactin level, clinical symptoms and the requirement of fertility, etc. Commonly used drugs include bromocriptine.