The survival time of patients with progressive myotonic dystrophy varies, with some patients dying of respiratory failure or heart failure in their 20s and a small number of patients living close to normal life years. Progressive myotonic dystrophy is a group of inherited muscle degenerative diseases characterized by slowly progressive, symmetric muscle weakness and atrophy without sensory impairment. The mode of inheritance is mainly autosomal dominant, stealth or X-linked. It can be classified into at least 9 types based on the mode of inheritance and age of onset, etc. Therefore, the lifespan varies depending on the typing. There is no specific treatment for progressive muscular dystrophy so far, only symptomatic treatment and supportive therapy. As there is no effective treatment, prenatal screening and prenatal diagnosis are essential. If the sick fetus is detected early, the pregnancy should be terminated to prevent the birth of the sick child, so as not to bring a huge burden to the family and society.