Psoriasis itch medications include antihistamines, glucocorticoids, vitamin D3 derivatives and so on. 1. Antihistamine drugs: they can directly antagonize H1 receptor and stabilize the activity of inflammatory cells, so as to stop itching, commonly used drugs are loratadine tablets, cetirizine hydrochloride tablets, etc. Glucocorticosteroids: they have the functions of anti-inflammation, anti-allergy and immunosuppression, which can also stop itching. 2. Glucocorticoid: anti-inflammatory, anti-allergic, immunosuppressive effect, can also play the effect of itching, commonly used drugs are dexamethasone acetate cream. 3. Vitamin D3 derivatives: can inhibit the proliferation of skin cells and induce their differentiation, can also play the effect of itching, commonly used drugs such as carbotriol cream. The use of the above drugs need to follow the doctor’s instructions, diagnosed with psoriasis, should be timely to the hospital, under the standardized guidance of a professional physician treatment, do not self-medication, in order to avoid adverse effects.