Nevus on testicle, usually pigmented nevus, does not have any significance, do not worry too much, patients are advised to consult with professional physicians for specific conditions. Pigmented nevus on testicle is mostly caused by local aggregation of melanocytes, if there is no progressive enlargement, no deepening of color and no change of morphology in the near future, it does not need too much intervention treatment. However, if the testicles are often rubbed, it is recommended to remove the nevus by surgery or laser treatment under the guidance of doctor. If the pigmented nevus increases in size, deepens in color, changes abruptly in shape or breaks down locally, the possibility of malignant transformation of the pigmented nevus is considered to be high, and it is recommended that the patient go to the dermatology department in time to consult the doctor, and under the doctor’s guidance, perform histopathological examination to determine whether malignant transformation exists, and if malignant transformation exists, the patient needs to perform surgical treatment, radiotherapy and so on, under the doctor’s guidance. Pigmented nevus can exist in any part of the body. Pigmented nevus located in the area of frequent friction, such as the pigmented nevus on the testicles, etc., is recommended to be treated with surgery or laser therapy under the guidance of a doctor.