Atrophic gastritis C2 belongs to moderate atrophic gastritis, and the treatment drugs mainly include acid inhibitors, antibiotics, gastric mucosal protectants, gastric motility promoters and so on. Atrophic gastritis C2 belongs to moderate atrophic gastritis. Patients with atrophic gastritis with Helicobacter pylori infection need to be treated with quadruple therapy, i.e., two antibiotics combined with proton pump inhibitors and bismuth, such as metronidazole, amoxicillin, bismuth potassium citrate and omeprazole. In addition, patients with moderate atrophic gastritis can also use gastric mucosal protectants and gastric stimulants, such as aluminum thioglycollate, Rebapatide, domperidone and so on. In daily life, patients with atrophic gastritis should have a regular diet, avoid overeating, and avoid drinking coffee, strong tea and alcohol. The above medications are recommended to be used under the guidance of a doctor. Patients diagnosed with atrophic gastritis C2 should be treated with medication under the guidance of a doctor.