Patient: Description (onset time, main symptoms, hospital visited, etc.): Hello doctor, I grew a nail-sized ringworm around my waist half a month ago, and a few days later grew a scaly red rash on my chest and abdomen, face and neck, flat and slightly itchy, went to the hospital dermatology department and said it was pityriasis rosea, but some doctors also suspect syphilis, please ask if pityriasis rosea is a symptom of syphilis? Take Chinese medicine, the effect is not good, the rash continues about half a month did not recede Want to get how to help: rose pityriasis is syphilis symptoms, what is the relationship between the two? A: Hello! First of all, talk about pityriasis rosea, it is a kind of skin performance produced by the interaction of our organism to endogenous allergens (in recent years more, think viral infection). Mostly manifested as the trunk, the proximal extremities erythema, plaques, scales, generally speaking most patients slightly itchy. The course of the disease is chronic and gradually increases to the distal extremities. Stage II syphilis rash occurs when the syphilis spirochete infection is untreated after unclean sexual intercourse, and the syphilis spirochete multiplies in about 6 weeks to 3 months and spreads to the whole body through the bloodstream, resulting in a visible rash. Stage II syphilis rash manifests in various forms, without pain or itching, with characteristic palmoplantar copper-red patches, collar-like scales, vulvar perianal flat warts, etc. More patients show an atypical trunk patch-like, papular, pustular syphilis rash, or lip or oral mucosal damage, or even diffuse hair loss. To distinguish these two diseases, pay attention to the history of unclean sexual contact 6 weeks ~ 3 months before the rash, the most important thing is to do blood RPR TPHA examination, if there is no history of unclean sexual contact, the laboratory test is negative, and the characteristics of the lesions of the trunk and limbs are consistent with the lesions of pityriasis rosea, then pityriasis rosea can be diagnosed and syphilis rash can be excluded.