The cause of high globulin in patients with cirrhosis is mainly the presence of chronic hepatitis, and the degree of globulin increase is related to the severity of chronic liver disease. Globulin is mainly produced due to lymphocytes. As long as inflammation exists in the body, increased globulin can occur, and as long as pathogens such as bacteria and viruses exist, they can stimulate lymphocytes to produce antibodies, which are mainly composed of globulin. For cirrhotic patients with elevated globulin, a decrease in albumin can be evident. After the decrease in albumin, cirrhotic patients will develop cirrhotic ascites and lower limb edema, etc. If necessary, intermittent infusion of albumin is needed to increase the colloid osmotic pressure, thus promoting the abdominal fluid to subside.