Pathologic fractures are fractures of the human skeleton caused by local bone lesions or systemic diseases that reduce the density of the bones with or without minor external forces. Pathological fractures are not uncommon in clinical practice, and they should be a complication of the primary disease. The most common sites of pathological fractures are the lower extremities such as the femur and tibia of the lower extremities, and in some cases, the upper extremities and clavicle-humerus fractures, and pathological fractures of the spine, most often in the lumbar vertebrae, which can also cause deformity and pain at the fracture site, and in severe cases, abnormalities such as limited movement of the pathological fracture site, and also bruises. Pathological fracture is still very dangerous, and it may affect the patient’s work and life, and even endanger the life, if malignant tumor, it may lead to other metastases, complications of pathological fracture such as nerve compression, tumor spread, and bleeding from the rupture of blood vessels at the fracture site, etc. For pathological fracture, imaging, nuclear bone scan, and pathological examination should be performed, and once it is determined Once a pathological fracture is identified, it is crucial to actively treat the primary disease that caused the pathological fracture and to prevent the fracture from reoccurring.