The symptoms of double upward gaze can be seen in epileptic-like seizures of hypoglycemia, mainly manifested as a shallow comatose state with moist, cyanotic skin, frothing at the corners of the mouth, double upward gaze, loss of light reflex in both pupils, neck tonicity, coarse breath sounds in both lungs, and strong heart sounds. The etiology of the symptoms of upward gaze of both eyes is mainly due to the severe glucose deficiency in the central nervous system and the reduced function of the higher centers to reduce the energy demand of brain tissue. If the hypoglycemic patient with loss of consciousness is not treated immediately, it can lead to seizures and irreversible neurological damage. The common ones are functional hypoglycemia and hepatic hypoglycemia, followed by hypoglycemia caused by insulinoma and other endocrine diseases. This disease is often misdiagnosed as hysteria, epilepsy, psychosis, brain tumor and encephalitis, etc.