The world’s first IVF case was born in 1978. In the last decade, IVF technology has become more and more perfect and generally accepted, and has now become a routine technique for treating infertility. This year the fertility centers have seen a rush of IVF consultations and visits. Xiao Li (pseudonym) and her sister-in-law are both new Shanghainese. After several years of hard work, their careers are now stable, but they have not been able to get pregnant. Xiao Li came to our fertility center at the beginning of this year. After a month of preparation, she went on the second cycle of IVF and transferred the embryos 3 days after egg retrieval and found a smooth pregnancy 2 weeks later. Sister-in-law, who is more than ten years older than Xiao Li and already almost 40 years old, first went to a tertiary specialist hospital in the city, where the doctor gave her the classic long protocol of ovulation promotion. However, after one fresh cycle and one thawing cycle transplant, she did not get pregnant and came to our fertility center this time. We evaluated her current situation, adjusted the ovulation protocol according to the response of the previous ovulation promotion, and her sister-in-law got pregnant in the same month of IVF! The ultrasound examination suggested twins. Citing this case is not to say that we are superior to others. In fact, the technology of IVF is relatively mature and the success rate of each fertility center does not differ much, the main reason affecting the pregnancy rate is the age of the woman. 25-29 years old is the best age for women to have children, of course, the success rate of IVF is the highest in this age group, up to 40-50%. However, women are like flowers, and although flowers are beautiful, they are short-lived. The quality of a woman’s egg cells decreases significantly after the age of 35, and the success rate of IVF decreases by more than half. In addition, each person is a unique individual and the process of IVF is both therapeutic and a process of exploring the most suitable ovulation protocol. The road to pregnancy may be rocky, but don’t get frustrated and give up in the face of setbacks, learn from Xiao Li’s sister-in-law, persevere, relax, actively cooperate with the doctor, find the right ovulation protocol for you, and eventually you can have your own baby.