Most of the testicular edema in patients with cirrhosis is due to testicular sphingomyelia. To consider the presence of ascites, severe hypoproteinemia, and the presence of infection, relevant tests such as liver function and abdominal and testicular ultrasound need to be improved. In case of hypoproteinemia, it is recommended to infuse albumin and apply diuretic drugs to promote the edema to subside, and in case of co-infection, it is recommended to apply anti-infective drugs to control the infection. It is common for patients with cirrhosis to develop edema, which is mainly related to portal hypertension, hypoproteinemia, sodium and water retention, etc. It is necessary to actively target medications for treatment, and patients with cirrhosis must be treated for the causes of cirrhosis, while paying attention to serious complications.