The use of macrolides, including azithromycin, when targeting a patient’s specific disease requires consideration of whether the patient has a respiratory mycoplasma infection or a genitourinary mycoplasma infection. Mycoplasma is a relatively small pathogenic microorganism in the body that usually causes disease in the respiratory and genitourinary systems. For respiratory system, the main symptoms are cough, coughing, low fever, malaise, etc. For urinary tract infection, the main symptoms are frequent, urgent, incomplete urination, lower abdomen, perineum, perianal swelling and other symptoms. Usually oral azithromycin, generally in about 5-7 days the symptoms can be relieved, but some patients friends are recurrent mycoplasma infections, need to find the foci as well as the female side of the treatment at the same time in order to avoid cross-infection.