Definition and assessment of dry weight, clinical significance 1. Definition of dry weight: It is the ideal weight when the patient feels comfortable and there is no excess water retention or dehydration in the body, and is a relative value. 2. Clinical significance of dry weight: Dry weight is an important indicator to assess the adequacy of dialysis. When dry weight is reached, rehydration blood pressure will drop, yawning, muscle cramps, vomiting and fainting will occur. Long-term dialysis dehydration without reaching dry weight will result in a series of manifestations of water retention, such as elevated blood pressure, edema of the lower limbs and face, and fluid accumulation in the body cavity, leading to the occurrence of serious comorbidities, such as acute heart failure, cerebral hemorrhage, and other life-threatening conditions. Therefore, the assessment of dry weight is a crucial link in the process of dialysis treatment. 3. Assessment of dry weight: In clinical practice, patients are usually evaluated by the following points to determine whether their dry weight is up to standard. Signs: Check the patient’s eyelids and both lower limbs with finger sunken edema, need to adjust the dry weight downward; until the edema disappears. According to the blood pressure, if the blood pressure is still not up to the standard with regular use of regular antihypertensive drugs, and the blood pressure usually reaches 160-180/90-100mmHg or more, there is water storage in the body, and the dry weight needs to be adjusted downward until the blood pressure drops to below 140/80mmHg. Diet and stool, if anorexia, reduced frequency of stool, constipation are present, water is stored in the body, and the dry weight should be adjusted downward until the symptoms disappear. Auxiliary examinations: If the above conditions occur, auxiliary examinations can be used to assess the dry weight, such as chest ultrasound to exclude pleural fluid, cardiac ultrasound to exclude pericardial effusion, chest X-ray to check cardiothoracic ratio <50% and no pulmonary stasis, abdominal plain film to exclude peritoneal effusion, etc. to set the dry weight. In addition, during the seasonal exchange, each time the increase or decrease of clothes should be weighed and informed to the physician in time to adjust the dry weight.