The principles of treatment for acute pancreatitis in children and adults are basically the same. Most children with acute pancreatitis can achieve good remission with conservative treatment. Fasting, gastrointestinal decompression, intravenous fluids and antispasmodic pain relief can be considered in the treatment process. Third-generation cephalosporins are generally recommended for the prevention and control of bacterial infections, which have fewer side effects and are more effective in children and can cross the blood-pancreatic barrier. If conservative treatment is not effective and the abdominal pain worsens, with clinical hyperthermia, the possibility of hemorrhagic necrotizing pancreatitis should be considered. In this case, timely surgical exploration should be considered to remove necrotic tissue and keep drainage open with timely flushing. In children with large pancreatic pseudocysts, elective jejunal drainage of the cyst should also be considered.