Patient Question: Description: Six courses of chemotherapy, chest and brain radiotherapy 25 times each Time: 2013-01-16 to 2013-10-09 Department: Tangshan Renmin Hospital, radiotherapy five Drug Name: Jianshuanyi kidney particles and Chinese medicine Serving Instructions: Taking almost a month, nausea, do not want to eat, temporarily stop taking After radiotherapy effect is quite good, tumor markers are normal, the primary tumor is also very stable, do ct shows liver has a shadow, consider the tumor, but did not affect the liver function, why do patients want to be in nausea, the local doctor said the liver tumor does not affect the appetite and nausea, why do patients appear nausea, appetite, and tumor markers are normal, the primary tumor is also very stable. The local doctor said that liver tumor does not affect loss of appetite and nausea, why does the patient have nausea and loss of appetite? Yan Dongjie, Department of Thoracic Surgery, Beijing Chest Hospital, Capital Medical University, replied: 1.Is the diagnosis of small cell lung cancer confirmed by pathology? 2. If the diagnosis has been confirmed, nausea and appetite may be caused by various factors, such as 1. brain metastasis, liver metastasis, mediastinal lymph node enlargement compressing the esophagus, abdominal lymph node metastasis and other occupying lesions, regardless of whether the liver function is normal or not, nausea and vomiting may occur. 2.Low protein, anemia, emaciation, cachexia state 3.Tumor released substances or metabolic waste cannot be eliminated in time through detoxification and excretion 4.Chemotherapy, Chinese medicine, nutrition and other drugs or food 3.Tumor markers from abnormal to normal can only indicate that the treatment is effective and cannot represent cure. Many patients’ tumor markers may be normal all the time. 4.Most of the lung cancer lesions cannot be eliminated by chemotherapy and radiotherapy, so the possibility of metastasis must exist, and the ways of metastasis are basically blood, lymph and direct implantation.