How to choose the combination of inhalation drugs scientifically and reasonably? In chronic obstructive pulmonary disease (stage II) or above, the degree of airflow restriction is more severe, and the clinical symptoms are more obvious and persistent, so it is necessary to combine two or more bronchodilators or bronchodilators with glucocorticosteroid treatment in the stable stage. Because of the combination treatment, the drugs used can play a synergistic role in different aspects to improve the efficacy. A lot of clinical experience has proved that combination therapy improves the quality of life, reduces acute attacks and keeps the disease relatively stable. And because the dose of each individual drug is not increased, the incidence of adverse reactions is not increased. At present, there are some inhalation drug combinations, the two inhalation drugs in the same container, so each inhalation can be inhaled at the same time two drugs. It is convenient to use, and it is not necessary to inhale two different drugs separately. More importantly, the efficacy is improved because the two drugs inhaled at the same time can be evenly distributed in the epithelial cells of the respiratory tract and have a greater effect. For example, Combivent aerosol (20 micrograms of ipratropium bromide/120 micrograms of salbutamol, nebulized inhalation (0.5 mg of ipratropium bromide/ 3 mg of salbutamol); Seretide dry powder inhalation (50 micrograms of salmeterol/ 100 micrograms of fluticasone); Symbicort dry powder inhalation (4.5 micrograms of formoterol/ 4.5 micrograms of budeson); Symbicort dry powder inhalation (4.5 micrograms of salmeterol/ 4.5 micrograms of budeson); Symbicort dry powder inhalation (4.5 micrograms of salmeterol/ 4.5 micrograms of budeson). 4.5 micrograms/budenolid 160 micrograms). The application of the above-mentioned drugs should be guided by a physician, including drug selection, dose and method of use, should be based on the condition, to develop specific measures suitable for the individual, and often contact with the physician, according to the condition to make adjustments, to ensure effective and safe treatment.