Mr. Sun was a patient admitted to the outpatient clinic. At that time, his blood potassium was low, and as a result, a thyroid nodule larger than 1 cm was found during the ultrasound of the thyroid gland, and he was advised to have a fine needle aspiration biopsy of the thyroid gland, which is the preferred gold standard for identifying benign and malignant nodules, as strongly recommended by both domestic and international guidelines for thyroid nodules. In order to prevent him and his family from unnecessary panic, we explained in detail the good prognosis of nail cancer and the need for long-term postoperative medical follow-up. Although the prognosis of nail cancer is good, it is inevitable that people will not panic because of the word “cancer” after all. Some tend to be benign, while others are prone to recurrence or metastasis. In general, the overall prognosis is good if detected early and if there are no local or lymph node metastases or distant metastases in the thyroid gland, i.e., if the risk of recurrence is stratified as low risk. As mentioned in the previous “Facing thyroid cancer together”, although the overall prognosis of thyroid cancer is very good, it can still be life-threatening in rare cases. The total recurrence rate was 23.5%. (J Clin Endocrinol Metab. 2001;86(4):1447-1463.) This is why surgery is only the beginning of treatment for nail cancer, and regular postoperative medical follow-up is the key to preventing recurrence. One of the patients who came for follow-up this morning had a single nodule with no metastasis or local infiltration, and was in the low-risk group for recurrence because he was young, so he was thought to be around 40 years old. The reason is that if we suppress thyroid function (thyroid function) to a lower level, the risk of recurrence is reduced, but the chance of side effects of the medication is also increased. The main drug used to suppress thyroid function is levothyroxine, and patients with thyroid cancer often require long-term use of levothyroxine at doses above the physiological dose, which, if controlled too low, can have the following side effects – 1. increased cardiac load and myocardial ischemia; 2. initiation or exacerbation of cardiac arrhythmias; 3. increased risk of hospitalization and death from cardiovascular events 4. increased bone loss, increased incidence of osteoporosis, and increased risk of fracture; if the drug exceeds the guideline recommendations, then we are paying a cardiovascular and bone loss price to prevent relapse, which large-scale evidence from interrogative medicine suggests is completely unnecessary; another situation is that the dosage is not enough, and the person just mentioned, at the time, was told to take 1 tablet orally plus three quarters of a tablet, and he ended up I told him to go back and add a quarter of a tablet, and he said, “Why don’t I just take 2 tablets, so I don’t have to break the tablets? This brings to mind the Chinese middle way, which shows that moderation is always the best thing. There is another story of insufficient dosage, it was a family member of a leader, who was also in the low risk group. At this time, only the physiological dose of substitution is needed, and there is no need to suppress the large dose of nail function. In fact, it is not necessary to add such a conservative amount slowly for young people and one year after nail cancer surgery, and as a result, only half a tablet was added, and the results were reviewed one month later, and the standard was still not reached. The target value for the second year after surgery is not the same as the first year. Finally, I hope all patients suffering from thyroid malignancy can monitor the relevant indicators regularly and live in peace with it, which requires you to take your medication on time, follow up regularly, and have good compliance, so that it will not affect your life expectancy and quality of life! May all families be happy and healthy! All the best for everyone! Enjoy the ease and beauty of each day!