Tongue and lips numbness may be caused by local stimulation (such as spicy food), oral diseases (such as oral mucosal inflammation), neurological diseases (such as cerebral infarction), etc., as follows. 1. Local stimulation: when we consume some spicy food, pepper, local stimulation of taste buds, resulting in numbness, prolonged smoking, muscle fatigue around the mouth, resulting in symptoms around the soreness and numbness. 2. Oral diseases: such as inflammation of the oral mucosa caused by infection, stimulation of the peripheral nerves, so that the nerve edema, resulting in numbness of the symptoms. 3. Neurological diseases: if the tongue and lips are numb, we need to be alert to the trigeminal neuropathy, cerebral infarction, intracranial tumor compression of the nerve. In the exclusion of local external stimuli, such as tongue and lip numbness symptoms, it is recommended to go to the hospital as soon as possible to consult a doctor to determine the cause of the disease and follow the doctor’s instructions for treatment.