Early medication for diabetes should be analyzed on a case-by-case basis. In the early stage of diabetes, drugs such as metformin and gliclazide can be taken orally, while diet should be strictly controlled and appropriate exercise should be carried out to achieve the purpose of lowering sugar. Metformin can improve insulin resistance and increase insulin sensitivity, thus improving and reversing glucose metabolism disorder. Gliclazide can promote the release of insulin, with obvious effect of lowering sugar. The use of Metformin and Gliclazide is prohibited in patients with severe hepatic or renal insufficiency, as well as in pregnant and lactating women. In addition, there are other hypoglycemic drugs, such as acarbose, etc. Diabetic patients should combine with their own conditions and choose reasonably under the guidance of doctors. All of the above drugs should be used under the guidance of a doctor, and should not be used without authorization to avoid adverse reactions, diabetic patients should go to the hospital in a timely manner, according to their own conditions, under the guidance of the doctor standardized treatment.