Contraindications to sartans include drug allergy, severe renal impairment, lactating pregnant women. 1. Allergy to drug components: patients who are allergic to any of the active ingredients of the drugs in the sartan class should be banned, which may lead to severe allergic reactions and even life-threatening. 2. Serious renal impairment: Sartan’s drugs can dilate the small glomerular arteries and reduce the glomerular filtration rate, which is contraindicated in patients with severe renal impairment, and may lead to aggravation of renal impairment, resulting in increased creatinine levels. 3. Pregnant lactating women: Sartan’s drugs may affect the development of the fetus and embryo, lactating pregnant women should be prohibited. Adverse effects of drugs of sartan are dizziness, nausea, flu-like symptoms, cough, bronchitis, elevated blood potassium, etc. The main indication for the drug is hypertension. Sartan drugs should be used under the guidance of a physician to master the indications and contraindications of the drug.