Fat grains are produced due to irritation of the epidermis. A small number of fat grains can be removed by picking with a sterile needle, while a large number of fat grains can be treated with laser and other methods. 1. Smaller number of fat grains: Patients first disinfect the local skin of the fat grains, then use a sterile syringe needle to gently puncture the fat grains, squeeze out the contents, and then use erythromycin ointment and other medications to apply, to prevent the emergence of infection. Erythromycin is prohibited for patients who are allergic to erythromycin. 2. The number of fat grains is large: it is recommended that patients go to the hospital to do laser method to remove, after the operation to do a good job of skin care, do a good job of sun protection measures. It is recommended that patients do not remove the fat grains at home by themselves, or there may be complications such as infection and bleeding, patients should go to the hospital in time for treatment.