To treat acne and blackheads on the face, different drugs should be chosen according to the severity of the condition. If the acne and blackheads on the face are relatively small, only topical drugs can be used, commonly used topical drugs include adapalene gel, tazarotene, isotretinoin, etc. The common adverse reactions to such drugs are easy local erythema and burning sensation, occasionally may appear skin flaking and other symptoms, not serious cases generally do not need to stop the drug, usually after two weeks of medication can gradually adapt. You can also choose to use topical anti-microbial drugs, such as erythromycin, clindamycin, chloramphenicol, fusidic acid, etc. If there are more facial acne and the condition is more severe, which means that the acne level exceeds grade II and reaches grade III-IV, you can take oral antibiotics, commonly used antibiotics such as minocycline, doxycycline, tetracycline, etc. You can also choose physical therapy such as red and blue light exposure. Also pay attention to eat more vegetables and fruits, control the intake of sweets as well as animal fatty, fried, spicy food, and strong alcohol. It is also important to choose the right facial cleanser and cosmetics according to your skin type and your doctor’s advice.