Children may develop fever after vaccination, for example, fever is often associated with BSE vaccination. Fever at this time is a normal immune response to vaccination and should not be a cause for concern, as symptomatic treatment is sufficient. Vaccination is a process to obtain an immune response by injecting inactivated bacteria or viruses. The immunizing agent of vaccination is a foreign stimulus to the organism, and it is some components of this pathogenic microorganism that stimulate the organism and cause fever in children. The physiological temperature usually does not exceed 38.5°C, and it mostly appears within one or two days after the vaccination. In clinical practice, especially in pediatric patients, the use of antipyretics is generally not recommended when the body temperature does not exceed 38.5°C. If the family meets this situation, first of all, do not be anxious, give the child more water at home, pay attention to the diet, you can use physical cooling methods to reduce fever, such as applying antipyretic patches or wiping with warm water. If the body temperature exceeds 38.5℃ and lasts for a longer period of time, it may be pathological. At this time, we should pay attention to it and go to the hospital in time to do some routine laboratory tests to find the cause of the disease and then treat it symptomatically. Fever is a common clinical manifestation after inoculation, so parents and children should not worry too much about it, and timely fever reduction and symptomatic treatment is sufficient. If the fever is recurrent or persistent, or if it is accompanied by other symptoms, it should be taken seriously enough to seek medical attention in a timely manner.