Staying up late with chest tightness and shortness of breath is mostly due to myocardial ischemia causing cardiac insufficiency, which results in the corresponding symptoms. Myocardial ischemia is a common disease is coronary heart disease, myocardial ischemia can also be caused by other diseases, such as myocarditis, cardiomyopathy and other diseases, staying up late often causes increased sympathetic excitability, which leads to increased blood pressure, thus causing the corresponding damage to blood vessels, and even the occurrence and development of coronary heart disease. The most common symptoms of coronary heart disease patients are chest pain, chest tightness, palpitations, and abnormal shortness of breath. Damage to the myocardium often causes cardiac insufficiency, which first manifests as exertional dyspnea and gradually develops paroxysmal dyspnea at night, telangiectatic breathing, and acute pulmonary edema state.