Postmenopausal vaginitis with metronidazole gel is possible to have discharge. Female friends after menopause due to the body’s estrogen level secretion decrease, will lead to vaginal dryness, vaginal normal flora disorders, which is easy to provoke secondary bacterial vaginitis. When bacterial vaginitis occurs, due to the stimulation of vaginal inflammation will cause fishy odor leukorrhea outflow, and accompanied by vulvar itching and other symptoms. When women suffer from bacterial vaginitis, they can use metronidazole gel to help treat it under the guidance of a doctor as appropriate, and after using metronidazole gel there is a possibility that a mixture of metronidazole gel and vaginal secretions may flow out. Therefore, postmenopausal vaginitis with metronidazole gel is possible after the discharge, it is recommended that female friends in the use of medication during the period, if there is special discomfort should also seek medical attention as soon as possible.