Prevention and treatment issues of retinitis pigmentosa

  Question: Is there a good treatment available? Is vitamin A palmitate the best drug available for the disease? Can it be cured? Is it able to make vision improve?  Answer: Retinitis pigmentosa is a complex genetic disease, and since it is a genetic disease, it cannot be cured without a fundamental modification of the body’s genes. But gene therapy is not easy. The damage of retinitis pigmentosa is located in the “cone cells” in the center of the retina in the early stage, and in the late stage, it develops to the “rod cells” around the retina and to the whole retina, and the role of vitamin A palmitate is to make light-sensitive pigments for the rod cells The role of vitamin A palmitate is to provide the raw material for the production of the photoreceptor pigment “retinal” in the retinal cells, so it is not a cure, nor does it slow down the progression of the disease, but only plays a role in the development of the lesion.  Question: Are vasodilators, vitamin B1 and B12 also effective? Do vasodilators have any side effects?  Answer: Vasodilators, vitamins B1 and B12 are efficacious because they improve the blood circulation in the retina and reopen the small occluded blood vessels. Vitamins B1 and B12 can provide nutrition for the optic nerve. Of course all these should be done under the guidance of a physician.  Question: Are there treatment options for retinitis pigmentosa complicated by cataracts and glaucoma? Or what medications can I take to delay and improve my current vision?  Answer: Retinitis pigmentosa complicated by cataract and secondary glaucoma can be treated. In the early stage, we can use eye drops to delay cataract. When the cataract reaches a certain level and threatens the visual function, it is medically known as “surgery indication”, then we need to do some tests to exclude “contraindication to surgery” and then we can choose surgery. However, due to the damage to the retinal photoreceptor system, post-operative vision is not as good as normal vision.  Question: Do patients with retinitis pigmentosa have to avoid bright light? Is it enough to go out with sunglasses?  Answer: Yes, patients with retinitis pigmentosa need to reduce bright light stimulation, and goggles are generally yellow and teal, not red, green, blue and other colors.