If the difficulty in urination is caused by acute urinary tract infection, it is recommended to give cephalosporin antibiotics or quinolone antibiotics for anti-infection treatment, commonly used drugs include cefoxitin sodium for injection, levofloxacin hydrochloride injection and other drugs. After the inflammation is controlled and the edema subsides, the difficulty in urination can be gradually relieved; 2. If the urinary tract is blocked suddenly due to urinary stones, it is recommended to temporarily give an indwelling catheter to relieve the difficulty in urination, give extracorporeal shock wave lithotripsy or give surgical treatment to remove the stones and restore the patency of the urinary tract, and the difficulty in urination can be relieved; 3. If the difficulty in urination is due to neurogenic bladder, it is recommended to leave the catheter in place temporarily. The nerve function will be restored gradually and the bladder contraction will be restored gradually, and the symptoms of difficult urination can be relieved.