Patients with high blood uric acid are suitable for running if there is no joint swelling and pain. However, attention should be paid to the appropriate amount of scientific running. High blood uric acid mostly triggers hyperuricemia, which is a disease caused by an imbalance in the body’s metabolism of uric acid, resulting in excessive accumulation of uric acid in the body, and is commonly found in people with alcoholism and obesity. Running is a convenient and fast mode of exercise, and hyperuricemia patients can maintain a healthy weight through running. However, if there are uncomfortable symptoms such as swollen joints and pain, you should seek medical advice and avoid running. Moderate-intensity aerobic exercise, such as jogging, is recommended for patients with high blood uric acid, and patients need to arrange their running schedules appropriately. Excessive exercise may lead to increased production of ketone bodies, which is not conducive to uric acid discharge and aggravates the condition. Attention should be paid to warming up before running to protect the joints. Patients with high uric acid are advised to go to the rheumatology and immunology departments of regular hospitals for detailed consultation and follow the doctor’s instructions for reasonable exercise.