Acute myocardial infarction combined with severe arrhythmia, need to perform electrical cardioversion to restore the heart rate, given to elevate blood pressure, improve cardiac function, antiplatelet therapy, if necessary, ventilator-assisted respiration, aortic balloon counterpulsation, early percutaneous coronary intervention. Acute myocardial infarction is easy to combine with severe arrhythmia, this situation is easy to appear hypotensive sudden death, should be given as soon as possible to electrical cardioversion reversal of malignant arrhythmia, for hypotension to give the application of antihypertensive drugs, early application of antiplatelet aggregation drugs and anticoagulants, if the condition of the critically ill need to be assisted by respiratory ventilation, balloon counterpulsation of aorta treatment of cardiac arrest, and so on. If the condition is relatively stable, early percutaneous intracoronary intervention to open the narrowed or occluded vessels can effectively prevent the progression of the disease and improve the prognosis. Acute myocardial infarction patients are in critical condition, sometimes easy to combine with serious arrhythmia, need to call 120 to the hospital as soon as possible to prevent delays in diagnosis and treatment.