Progesterone, a natural progesterone secreted by the corpus luteum of the ovary, is important for women as it protects the lining of the uterus and helps provide an environment conducive to successful conception and a healthy pregnancy. A woman’s uterine health can be clinically determined by normal progesterone values. After pregnancy, the progesterone level in the body will show a continuous increase due to the continued production of progesterone by the corpus luteum of the ovaries. It generally increases with the week of pregnancy, but there are some differences between individuals. In general, progesterone levels range from 16.9-32.1 ng/ml in the 7th week of pregnancy; 25-51 ng/ml in the 9th-12th weeks of pregnancy; and 75.2-146.6 ng/ml in the 21st-24th weeks of pregnancy. Progesterone levels are associated with the outcome of early pregnancy, and women with embryonic arrest and ectopic pregnancy have significantly lower serum progesterone levels than patients with preterm abortion and normal early pregnancy. Progesterone in the range of 15-25 ng/mL has a pregnancy outcome that is essentially intrauterine, but is prone to early preterm abortion. With progesterone less than 15ng/mL, the pregnancy outcome is more likely to be ectopic pregnancy or indolent abortion. If the progesterone is more than 25ng/mL, the pregnancy outcome is mostly normal intrauterine pregnancy, and some of them have pre-eclampsia, but most of them can continue the pregnancy after giving supplemental luteal function. In conclusion, close monitoring of progesterone indicators during pregnancy is particularly important and it is recommended to pay sufficient attention to it.