Chemotherapy is now one of the main methods of treating tumors. It plays a great role in controlling the disease development and improving the patient’s symptoms. However, while chemotherapy drugs inhibit or kill abnormal cells, they also have toxic effects on normal cells in the organism. The most common are as follows: First, the most common is leukopenia, before and after chemotherapy need to review the blood routine, if lowered in time to give whitening drugs to avoid serious complications such as infection. Second, gastrointestinal reactions: manifested as loss of appetite, nausea and vomiting or diarrhea. During chemotherapy, the diet should be hygienic, light and nutritious food, encourage patients to eat more, eat less and more, eat their favorite food. If vomiting is heavy and affects eating, promptly inform the doctor and administer infusion therapy. There are better antiemetic drugs available, which can greatly reduce the gastrointestinal reaction, and individual differences between patients, the degree of nausea and vomiting varies, so do not equate chemotherapy with vomiting and avoid self-suggestion. In addition, we should also pay attention to oral hygiene and insist on rinsing our mouth after each meal to avoid oral ulcers. If diarrhea occurs during chemotherapy, especially if it exceeds 5 times a day, you should tell your doctor promptly. Third, dull or abnormal sensation, such as numbness at the ends of the limbs, aggravated by cold, so attention should be paid to prohibit cold water washing, brushing teeth, washing feet and cold diet, avoid contact with cold objects, pay attention to warmth. In short, chemotherapy patients are in a low immune function, so they should regulate their emotions, avoid worry, distress or impatience, and cooperate with doctors to complete the chemotherapy plan.