Chest tightness like taking capsules that cannot be swallowed may be related to lung infection, esophageal stenosis, esophageal cancer and other diseases. 1. Lung infection: Lung infection is an infectious disease of the respiratory system caused by bacteria or viruses, which manifests itself as coughing, coughing up sputum and fever, etc. Lung infection is serious and will cause chest tightness, shortness of breath, difficulty in swallowing, etc., which will have a serious impact on the body. 2. Esophageal stenosis: caused by esophageal injury, infection, etc., or scar tissue caused by swallowing corrosive substances, it is a disease manifested by difficulty in swallowing. Esophageal stenosis will cause chest tightness and difficulty in swallowing, and the symptoms will get worse with the progress of the disease. 3. Esophageal cancer: it is a kind of malignant tumor originated from esophagus, often occurring in the middle part of esophagus. Its main manifestations are progressive dysphagia, chest tightness, obvious sternal pain, and difficulty in eating soft food and drinking water in the late stage. If there is chest tightness that can’t be swallowed by eating capsules, you should consult a doctor in time to find out the cause of the disease and treat the symptoms.