Corticosteroids include hydrocortisone, prednisone, methylprednisolone, and dexamethasone. Adrenocorticotropic hormones, which can be abbreviated as corticosteroids, are steroids and are a general term for hormones secreted by the adrenal cortex. The outermost layer of the adrenal cortex can synthesize salt corticosteroids such as aldosterone and 11-deoxycorticosterone; the middle layer of the zona fasciculata can synthesize glucocorticoids such as hydrocortisone and cortisone; and the inner layer of the zona reticularis can synthesize sex hormones in trace amounts. However, clinically used corticosteroid drugs are mainly glucocorticosteroids, including short-acting, intermediate-acting and long-acting drugs. The target cells of glucocorticoid drugs are mainly distributed in the lungs, brain, liver, bone, skeletal muscle, gastrointestinal smooth muscle, lymphatic tissues and other parts of the body, and common adverse reactions include adrenocortical dysfunction, obesity, full-moon face, buffalo back, osteoporosis and so on. Pregnant women need to use glucocorticoids with caution; long-term use in elderly patients is prone to hypertension, osteoporosis, etc., need to be standardized under the guidance of a doctor.