In the last decade, voice diseases have gradually been given renewed attention as people’s demand for voice has also increased. Among the voice diseases, Renk’s edema (Reinke’s layer edema is a diffuse retention of protein matrix in the superficial lamina propria of the vocal folds bilaterally) is a common disease. This disease was studied by Hajek M and Reinke F as early as 1891 and 1895, respectively. The clinical manifestations of the disease are mainly hoarseness, low pitch and dull tone, mostly with a history of recent exacerbations, and in severe cases, voice loss. Indirect laryngoscopy reveals glossy edema of the vocal cords; electronic laryngoscopy reveals polyp-like, translucent, fish-belly-like swelling of the vocal cords surface bilaterally or unilaterally. The grading of Renk edema is divided into three levels according to the severity of the lesion: grade I bilateral anterior 1/3 contact of the vocal folds, grade II bilateral anterior 2/3 contact of the vocal folds, and grade III bilateral full-length contact of the vocal folds. This researcher has accumulated many years of experience and has summarized a set of effective methods, which have achieved good results. The criteria for determining the efficacy are: cure: the symptoms of hoarseness and low tone disappear, the tone quality returns to normal, the vocal fold edema disappears, and the edges are neat and smooth; improvement: the symptoms of hoarseness and low tone are reduced, the tone quality improves, and the vocal fold edema is significantly reduced; invalid: the symptoms of hoarseness and low tone do not improve, and the vocal fold is still edematous. Specific points: 1. comprehensive treatment in the perioperative period; 2. application of the technique of external vocal fold microflap under TV laryngoscopy; 3. application of difficult vocal fold exposure technique under general anesthesia. TV laryngoscopic lateral vocal fold microflap technique: 6.5-gauge tracheal intubation, inhalation intravenous compound anesthesia. A support laryngoscope is inserted through the oral cavity to expose the vocal fold, the support laryngoscope is adjusted and fixed, a 0° endolaryngoscope is inserted into the lateral hole of the support laryngoscope, and the lens is adjusted to give a clear and magnified image of the surgical field on the monitor. The posterolateral microflap technique is used under monitor screen surveillance. The location of the incision and the method of incision are determined with a laryngeal knife on the lateral side of the vocal cord according to the degree of edema; if the edema is mild, an incision parallel to the free edge of the vocal cord can be made 2-3 mm lateral to the vocal cord to incise the edematous mucosa, preserving as much as possible the anterior joint mucosa, turning over the mucosa, exposing the superficial lamina propria of the edema, aspirating the retained jelly-like material, and preserving the medial mucosa and part of the superficial lamina propria of the vocal cord. Then the mucosa was covered on the surface of the vocal cord; if the edema was heavy, a shuttle incision could be made on the lateral side of the vocal cord to remove the excess mucosa first, and other methods were the same; finally, the laryngeal endoscope was inserted into the supporting laryngoscope for examination of the laryngeal chambers and subglottic area for lesions. After surgery, all specimens were sent for pathological examination.