The side effects mentioned in the instructions for the use of prednisone are: Cushing’s syndrome caused by prolonged heavy use, induced neuropsychiatric symptoms as well as peptic ulcers, osteoporosis, suppressed growth and development, and concurrent and aggravated infections. Here is a slight explanation, no one gives an exact definition of what is long-term. Generally speaking, hormones are used for a short period of time, within 5 days, and regular doses of hormones do not cause significant side effects to the body. Beyond 1 week, adrenocortical function can be suppressed and side effects may be induced. Cushing’s syndrome is commonly referred to as fat gain, caused by fat redistribution; induced neuropsychiatric symptoms are excitement, insomnia, and even psychiatric problems. Perhaps a better understanding of side effects might be achieved by first looking at what the pharmacopoeia says about contraindications to hormones: 1. history of severe psychiatric disease; 2. active gastric and duodenal ulcers; 3. recent post-gastrointestinal anastomosis; 4. severe osteoporosis; 5. significant diabetes; 6. severe hypertension; 7. viral, bacterial, or fungal infections that cannot be controlled with antibacterial drugs; 8. hepatic insufficiency, as prednisone Need to be metabolized by the liver to prednisolone before it takes effect. See this should understand that hormones can aggravate these diseases, or may have induced these diseases, that is, the side effects of hormones. Therefore, the pharmacopoeia also stipulates that it is better not to use or delay the use of hormones for the following diseases: 1, acute heart failure or other heart disease; 2, diabetes; 3, diverticulitis; 4, emotional instability and psychotic tendencies; 5, systemic fungal infections; 6, glaucoma; 7, hyperlipoproteinemia; 8, hypertension; 9, hypothyroidism (when the effect of glucocorticoids is enhanced); 10, osteoporosis; 11, gastric ulcer, gastritis or esophagitis; 12, renal impairment or stones; 13, tuberculosis; 14, pregnant and lactating women; 15, active gastroduodenal ulcer; 16, after recent gastrointestinal anastomosis; 17, more severe osteoporosis; 18, prednisone does not treat inflammatory infections, its reduced inflammatory response, easy to mask the symptoms, the application of prednisone at the same time must apply a sufficient amount of effective 19, long-term use of prednisone patients in the event of surgery, trauma and other stress, the dose should be increased short-term; 20, surgical patients using prednisone affect wound healing, it is best not to use. Of course, it should be noted that some side effects do not occur in all people, such as hypertension and diabetes, which can only be treated by follow-up observation, but not prevented. However, some side effects, such as gastroduodenal ulcer, can be prevented with acid suppressants or mucosal protectors. All side effects require mutual communication between patients and doctors and close follow-up before the harm of side effects can be minimized. Therefore, when using hormones, care must be taken to consider the pros and cons. Not all idiopathic interstitial pneumonia requires hormone therapy, and even if it is used, it should be followed and observed by an experienced physician.