World Inflammatory Bowel Disease Day: Although a rare disease, the incidence is increasing every year May 19 is World Inflammatory Bowel Disease Day. Although inflammatory bowel disease is a “rare disease” category, specifically: “Ulcerative colitis and Crohn’s disease are both on a significant year-on-year increase, which is a linear trend. Statistics show that there are at least five million patients with inflammatory bowel disease worldwide. In China, the total number of inflammatory bowel disease cases in the last 10 years is about 350,000. It is noteworthy that the number of patients is increasing year by year, compared with the previous 10 years, the total number of inflammatory bowel disease cases in the last 10 years has increased about more than 24 times, among them, the number of Crohn’s disease patients has increased even more than 15 times, these figures sound an alarm for us, and the public should understand and pay attention to inflammatory bowel disease early. Inflammatory bowel diseases include Crohn’s disease and ulcerative colitis, both of which affect the digestive system and cause inflammation, ulceration and bleeding of the intestinal tissues. The causes of inflammatory bowel disease are not well understood and may include genetics, food allergies, and environmental factors. The two diseases, Crohn’s disease and ulcerative colitis, are not quite the same, but both primarily affect the intestinal mucosa, leading to inflammation, erosion, ulceration and hemorrhage in the intestine, with symptoms such as stomach pain, diarrhea and blood in the stool.” Patients with Crohn’s disease often suffer from stress and pain both physically and psychologically, calling attention to their gastrointestinal health, early intervention will be effective in alleviating the condition and effective treatment. “Crohn’s disease is a long-term chronic disease that has a significant impact on patients’ work and life, as well as placing a psychological burden on the patient. In addition, Crohn’s disease has a long-term impact on the patient’s family and on society.” “As long as it can be diagnosed early and given proper treatment, it can be controlled because it is a chronic, benign, inflammatory disease, so it is very important for the disease to be correctly known, correctly diagnosed and correctly treated.” “Crohn’s disease patients with repeated inflammation of the intestine, repeated removal, resulting in the intestine will be short, the intestinal function will be affected, absorption, secretion, movement of these functions are no longer, it will cause the loss of normal physiological functions of the human body, the so-called disability is such that there is more or less reduction in the function of the intestine, of course, the disease may also have other complications. “ When talking about the treatment of Crohn’s disease, several experts pointed out that the main goal of treatment of Crohn’s disease at present is to achieve mucosal healing. The importance of early intervention therapy and the advantages of biologic treatment modalities were emphasized: “Mucosal healing means that not only the patient’s symptoms should be relieved, but also the active inflammation of the intestine should disappear. If such a treatment goal can be achieved, the patient’s future recurrence rate is also greatly reduced, and the surgery rate can be greatly reduced. If anti-TNF-α biologics are given early, many patients can achieve the goal of mucosal healing and long-term maintenance. World Inflammatory Bowel Disease Day (World IBDDay), celebrated annually on May 19, is the most influential global day for the inflammatory bowel disease community, with professional and patient organizations from 36 countries on four continents joining in the global activities on May 19 each year.