What are the frequent causes of elevated transaminases in fatty liver? Fatty liver is the result of excessive fat accumulation in the liver, which causes damage to liver cells. Fatty liver can be classified as mild, moderate or severe by the degree of liver cell damage and the amount of fat accumulation. Generally speaking, patients with mild fatty liver are often in the early stage of hepatocellular damage, at this time, hepatocytes have a strong compensatory capacity generally does not cause a significant increase in transaminases, this stage often leads patients to ignore the progress of the disease, but patients can confirm the diagnosis of mild fatty liver through liver ultrasound. As the accumulation of fat in the liver worsens, patients with mild fatty liver will slowly turn into moderate or severe fatty liver, when the liver cell damage deteriorates further and the transaminases synthesized by the liver cells are slowly released into the blood, resulting in a significant increase in serum transaminases. Among them, the transaminase index of patients with severe fatty liver can be more than 3-5 times higher than normal. These are the common causes of elevated aminotransferases caused by fatty liver. In fact, patients with mild fatty liver should not worry too much, as they can avoid further damage to liver cells through diet control, proper exercise and a good rest and relaxation schedule, so that mild fatty liver can be completely restored to normal. Once the patient’s condition has progressed to moderate or severe fatty liver, it is often necessary to protect liver function by adjusting the diet, work and rest schedule, and strengthening exercise in conjunction with drug therapy.