There are many reasons for itchy hands and feet, and the following reasons are often seen in clinical practice: First, consider eczema dermatitis, acute eczema will appear localized erythema, papules, blisters, accompanied by intense itching. You can apply petroleum jelly topically to moisturize, avoid hot water, avoid scrubbing with alkaline soap; second, fungal infection, fungal infection will lead to local itching of the skin, blisters or flaking, then you need to go to the hospital to do fungal immunofluorescence examination to confirm the diagnosis of fungal infection, you can topical antifungal treatment with Dakine cream; third, contact dermatitis, contact allergies, possibly contact with chemicals, dust, new environment will appear localized peeling, dry cracking, itching, this time you need to check the allergen, know what to be allergic to, in order to avoid similar situations in future life.