1, hypertension, hyperlipidemia, atherosclerosis factors: the onset of trigeminal neuralgia is proportional to age, as age increases, the curvature of blood vessels will increase and the elasticity of blood vessels will gradually decrease, while hypertension, hyperlipidemia, atherosclerosis and other factors will accelerate this progress. Clinically observed atherosclerotic vessels or vascular collaterals near the trigeminal nerve, sometimes with calcification on the vessel wall, are often the cause of trigeminal neuralgia. 2, paranasal sinusitis, odontogenic inflammatory factors: inflammatory lesions occur in the face, nasal cavity and oral cavity innervated by the trigeminal nerve, such as paranasal sinusitis, odontogenic inflammation, etc., which can form long-term chronic stimulation, thus leading to trigeminal nerve dysfunction and the occurrence of trigeminal neuralgia. 3, viral infection: herpes and herpes simplex virus infection, similar to the flu, the facial skin appears clustered blistering rash, the virus can invade the cranium along the trigeminal nerve pathway and latent in the trigeminal ganglion, thus causing trigeminal neuralgia. 4, Bone hyperplasia and trauma cause narrowing of the bone canal of the trigeminal nerve pathway: round hole and oval foramen are the bone canals of the second and third cranial expenditures of the trigeminal nerve, bone hyperplasia or hyperplasia caused by inflammation of the periosteum can narrow the bone canal; maxillofacial and craniofacial injuries cause fractures at the base of the skull, which can also cause narrowing of this bone canal. 5.Dental system dysfunction: such as early cusp contact, severe locking, missing posterior teeth or excessive wear of the occlusal surface, etc., can spasm the muscle groups around the mandibular joint, thus inducing trigeminal neuralgia.